• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: STAT5{A,B}.p2

Z-value: 1.570

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr19_+_49180171	3.755	NM_003445 NM_198089	ZNF155	zinc finger protein 155
chr19_+_49248003	3.619	NM_013361	ZNF223	zinc finger protein 223
chr19_+_49408523	2.572	NM_182490	ZNF227	zinc finger protein 227
chr19_+_49361054	2.270	NM_001146220 NM_001032373 NM_001032374 NM_015919 NM_001032372	ZNF226	zinc finger protein 226
chr19_+_49221333	2.184	NM_001129996 NM_013360	ZNF284 ZNF222	zinc finger protein 284 zinc finger protein 222
chr9_-_114814286	1.972	NM_001101338	ZNF883	zinc finger protein 883
chr19_+_61798434	1.813	NM_021216	ZNF71	zinc finger protein 71
chr19_+_49290319	1.791	NM_013398	ZNF224	zinc finger protein 224
chr5_+_150008030	1.731		SYNPO	synaptopodin
chr7_+_89870647	1.644	NM_001185072 NM_001185073 NM_012129	CLDN12	claudin 12
chr7_+_89870707	1.631		CLDN12	claudin 12
chr19_-_49097774	1.589		LOC100505715	hypothetical LOC100505715
chr17_+_36665161	1.541	NM_030975	KRTAP9-9	keratin associated protein 9-9
chr19_+_49309350	1.529	NM_013362	ZNF225	zinc finger protein 225
chr4_+_86615275	1.492	NM_001025616	ARHGAP24	Rho GTPase activating protein 24
chr18_+_54958095	1.452	NM_033280	SEC11C	SEC11 homolog C (S. cerevisiae)
chr10_-_121345968	1.425		TIAL1	TIA1 cytotoxic granule-associated RNA binding protein-like 1
chr3_+_171422940	1.418		PRKCI	protein kinase C, iota
chr19_-_41849558	1.417	NM_153257	ZNF461	zinc finger protein 461
chr15_+_88696480	1.375	NM_001004309	ZNF774	zinc finger protein 774
chrX_+_105932536	1.363	NM_017752 NM_198881	TBC1D8B	TBC1 domain family, member 8B (with GRAM domain)
chr20_-_25625173	1.342	NM_015655	ZNF337	zinc finger protein 337
chr3_+_171422917	1.326		PRKCI	protein kinase C, iota
chr3_+_171422908	1.294	NM_002740	PRKCI	protein kinase C, iota
chr19_+_49023283	1.281	NM_181845	ZNF283	zinc finger protein 283
chr19_-_63018092	1.271	NM_024762	ZNF552	zinc finger protein 552
chr8_-_101384633	1.206	NM_015435	RNF19A	ring finger protein 19A
chr19_-_49696322	1.168	NM_013256	ZNF180	zinc finger protein 180
chr19_-_49309102	1.131		LOC100379224	hypothetical LOC100379224
chr5_+_57914658	1.096	NM_138453	RAB3C	RAB3C, member RAS oncogene family
chr19_+_58715988	1.084	NM_018555	ZNF331	zinc finger protein 331
chr16_-_219339	1.080	NM_018032 NM_201412	LUC7L	LUC7-like (S. cerevisiae)
chr19_+_49147219	1.077	NM_013359	ZNF221	zinc finger protein 221
chr3_+_197951121	1.066	NM_002577	PAK2	p21 protein (Cdc42/Rac)-activated kinase 2
chr17_-_18526296	1.060	NM_001145045	ZNF286B	zinc finger protein 286B
chr19_+_49198916	1.060	NM_006300	ZNF230	zinc finger protein 230
chr16_-_219111	1.052
chr15_+_20384835	1.046	NM_001102610 NM_052903	TUBGCP5	tubulin, gamma complex associated protein 5
chr10_-_98315090	1.028		TM9SF3	transmembrane 9 superfamily member 3
chr19_-_62680703	1.017	NM_001024596 NM_001144068	ZNF772	zinc finger protein 772
chr10_+_124903874	1.001		BUB3	budding uninhibited by benzimidazoles 3 homolog (yeast)
chr9_-_103185621	0.976	NM_001127610	BAAT	bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr14_-_19951417	0.941	NM_007110	TEP1	telomerase-associated protein 1
chr19_-_49552638	0.935	NM_001083335 NM_013380	ZFP112	zinc finger protein 112 homolog (mouse)
chr17_-_44847215	0.935	NM_002634	PHB	prohibitin
chr16_+_52295545	0.929		FTO	fat mass and obesity associated
chr3_+_197951203	0.929		PAK2	p21 protein (Cdc42/Rac)-activated kinase 2
chr17_-_44847214	0.928		PHB	prohibitin
chr19_-_61874934	0.921		ZNF835	zinc finger protein 835
chr6_+_84626113	0.919		CYB5R4	cytochrome b5 reductase 4
chr17_+_15543771	0.908		ZNF286A	zinc finger protein 286A
chr18_-_41938196	0.905	NM_001001937	ATP5A1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr6_+_84626146	0.893		CYB5R4	cytochrome b5 reductase 4
chr11_-_82675024	0.887	NM_021825	CCDC90B	coiled-coil domain containing 90B
chr19_-_62782066	0.868		ZNF416	zinc finger protein 416
chr18_+_41938295	0.856	NM_138443	HAUS1	HAUS augmin-like complex, subunit 1
chr19_+_39860398	0.856	NM_001012320 NM_018443	ZNF302	zinc finger protein 302
chr14_-_76958984	0.855	NM_138791 NM_001113475	C14orf148	chromosome 14 open reading frame 148
chr13_-_98202884	0.852	NM_005073	SLC15A1	solute carrier family 15 (oligopeptide transporter), member 1
chr5_+_147695314	0.844	NM_001040433	SPINK9	serine peptidase inhibitor, Kazal type 9
chr19_-_49131250	0.838	NM_003425	ZNF45	zinc finger protein 45
chr19_+_42400908	0.792		ZNF383	zinc finger protein 383
chr7_-_132417374	0.789		CHCHD3	coiled-coil-helix-coiled-coil-helix domain containing 3
chr19_-_61596681	0.789	NM_144690	ZNF582	zinc finger protein 582
chr19_+_42033106	0.784	NM_003419	ZNF345	zinc finger protein 345
chr3_+_140545528	0.766	NM_020191	MRPS22	mitochondrial ribosomal protein S22
chr12_+_132167551	0.758		ZNF140	zinc finger protein 140
chr19_+_42033564	0.754		ZNF345	zinc finger protein 345
chr19_+_49268106	0.746	NM_001037813	ZNF284	zinc finger protein 284
chr19_+_62972861	0.745		ZNF586	zinc finger protein 586
chr6_-_27548438	0.737	NM_007149	ZNF184	zinc finger protein 184
chrX_-_154216929	0.730	NM_001289	CLIC2	chloride intracellular channel 2
chr18_-_45241014	0.724	NM_017653	DYM	dymeclin
chr6_+_84626083	0.717	NM_016230	CYB5R4	cytochrome b5 reductase 4
chr2_+_88772281	0.716	NM_144563	RPIA	ribose 5-phosphate isomerase A
chr19_-_39859997	0.709
chr12_+_132167512	0.701		ZNF140	zinc finger protein 140
chr5_+_145297490	0.697		SH3RF2	SH3 domain containing ring finger 2
chr12_+_11694172	0.695		ETV6	ets variant 6
chr19_+_9112052	0.687	NM_001190791 NM_020933	ZNF317	zinc finger protein 317
chr6_-_30766621	0.683	NM_007243	NRM	nurim (nuclear envelope membrane protein)
chr7_-_93471463	0.669	NM_005868	BET1	blocked early in transport 1 homolog (S. cerevisiae)
chr6_+_100075572	0.667	NM_001195131	LOC100130890	hypothetical protein LOC100130890
chr11_-_123918759	0.662	NM_001005195	OR8B12	olfactory receptor, family 8, subfamily B, member 12
chrX_-_139694248	0.658	NM_004065	CDR1	cerebellar degeneration-related protein 1, 34kDa
chr19_-_42098758	0.657	NM_001171979	ZNF829	zinc finger protein 829
chr11_+_36572615	0.653	NM_138787	C11orf74	chromosome 11 open reading frame 74
chr4_+_157044296	0.648	NM_005651	TDO2	tryptophan 2,3-dioxygenase
chr19_+_42099073	0.642	NM_198539	ZNF568	zinc finger protein 568
chr17_+_36636404	0.642	NM_031961	KRTAP9-2	keratin associated protein 9-2
chr1_+_40769877	0.640		ZNF684	zinc finger protein 684
chr11_-_82674546	0.639		CCDC90B	coiled-coil domain containing 90B
chr19_+_49337568	0.633		ZNF234	zinc finger protein 234
chr3_-_185218311	0.631	NM_001023587 NM_005688	ABCC5	ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr19_-_62781883	0.628	NM_017879	ZNF416	zinc finger protein 416
chr9_-_98656206	0.626	NM_001001662	ZNF782	zinc finger protein 782
chr9_-_133945064	0.619	NM_004269	CRSP8P MED27	mediator complex subunit 27 pseudogene mediator complex subunit 27
chr19_+_49337548	0.618	NM_001144824 NM_006630	ZNF234	zinc finger protein 234
chr8_+_124154117	0.618		WDR67	WD repeat domain 67
chr3_-_120861959	0.614	NM_022135	POPDC2	popeye domain containing 2
chr3_+_58459131	0.606	NM_153331	KCTD6	potassium channel tetramerisation domain containing 6
chr19_+_62972808	0.597	NM_017652	ZNF586	zinc finger protein 586
chr14_+_67356248	0.593	NM_002877 NM_133509 NM_133510	RAD51L1	RAD51-like 1 (S. cerevisiae)
chr16_-_52295214	0.586	NM_001127897 NM_015272	RPGRIP1L	RPGRIP1-like
chr19_+_49455872	0.582	NM_181756	ZNF233	zinc finger protein 233
chr6_+_139136349	0.577	NM_015439	CCDC28A	coiled-coil domain containing 28A
chr11_-_125278296	0.574	NM_031307	PUS3	pseudouridylate synthase 3
chr8_+_124154079	0.568	NM_001145088 NM_145647	WDR67	WD repeat domain 67
chr14_-_69953433	0.567	NM_018373	SYNJ2BP	synaptojanin 2 binding protein
chr5_+_85949511	0.555		COX7C	cytochrome c oxidase subunit VIIc
chr15_+_39853982	0.548		MAPKBP1	mitogen-activated protein kinase binding protein 1
chr5_+_14493905	0.547		TRIO	triple functional domain (PTPRF interacting)
chr3_+_132228383	0.541	NM_001146003 NM_024800 NM_145910	NEK11	NIMA (never in mitosis gene a)- related kinase 11
chr12_+_132167057	0.540	NM_003440	ZNF140	zinc finger protein 140
chr19_-_49500966	0.505	NM_004234	ZNF235	zinc finger protein 235
chr5_-_178090203	0.504	NM_005649	ZNF354A	zinc finger protein 354A
chr4_+_24987914	0.487	NM_013367	ANAPC4	anaphase promoting complex subunit 4
chr20_+_39091026	0.486		TOP1	topoisomerase (DNA) I
chr15_+_39853923	0.477	NM_001128608 NM_014994	MAPKBP1	mitogen-activated protein kinase binding protein 1
chr19_+_63611930	0.468		ZNF584	zinc finger protein 584
chr3_+_181802592	0.460	NM_001042601 NM_133462	TTC14	tetratricopeptide repeat domain 14
chr1_+_93418866	0.444		CCDC18	coiled-coil domain containing 18
chr8_-_99375739	0.441	NM_024759	NIPAL2	NIPA-like domain containing 2
chr14_-_67232172	0.440	NM_016026	RDH11	retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
chr5_+_178219519	0.436	NM_058230	ZNF354B	zinc finger protein 354B
chr19_-_42098919	0.434	NM_001037232	ZNF829	zinc finger protein 829
chr19_+_42553895	0.433	NM_032453	ZNF527	zinc finger protein 527
chr1_-_33275015	0.429		AK2	adenylate kinase 2
chr13_+_114098045	0.423	NM_001164144 NM_001164145 NM_032436	ZNF828	zinc finger protein 828
chr4_-_89299034	0.418	NM_004827	ABCG2	ATP-binding cassette, sub-family G (WHITE), member 2
chr4_+_130236731	0.414	NM_001099783	C4orf33	chromosome 4 open reading frame 33
chr9_-_133944877	0.411		MED27	mediator complex subunit 27
chr1_+_40769819	0.411	NM_152373	ZNF684	zinc finger protein 684
chr17_+_15543615	0.407	NM_001130842 NM_020652	ZNF286A	zinc finger protein 286A
chr5_+_85949518	0.406	NM_001867	COX7C	cytochrome c oxidase subunit VIIc
chr3_+_123882355	0.392	NM_017554	PARP14	poly (ADP-ribose) polymerase family, member 14
chr1_-_33275051	0.385		AK2	adenylate kinase 2
chr8_-_144770764	0.370		TSTA3	tissue specific transplantation antigen P35B
chr1_-_33275039	0.368		AK2	adenylate kinase 2
chr10_+_93548048	0.363		TNKS2	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr1_-_33275071	0.355	NM_013411	AK2	adenylate kinase 2
chr9_-_103200697	0.345	NM_019051	MRPL50	mitochondrial ribosomal protein L50
chr19_-_4853878	0.340	NM_001080523	ARRDC5	arrestin domain containing 5
chr12_+_12857516	0.338	NM_016355 NM_201224	DDX47	DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
chr9_+_103200939	0.338	NM_003452 NM_197977	ZNF189	zinc finger protein 189
chr19_-_41955493	0.337	NM_001193552	ZNF850	zinc finger protein 850
chr1_-_246804680	0.337	NM_001001821	OR2T34	olfactory receptor, family 2, subfamily T, member 34
chr3_+_51870684	0.322	NM_203424	IQCF2	IQ motif containing F2
chr10_+_93548162	0.322		TNKS2	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr17_+_29606408	0.318	NM_002982	CCL2	chemokine (C-C motif) ligand 2
chr20_-_18425811	0.317	NM_006606	RBBP9	retinoblastoma binding protein 9
chr19_+_63611819	0.317	NM_173548	ZNF584	zinc finger protein 584
chr11_+_4522993	0.316	NM_001004137	OR52M1	olfactory receptor, family 52, subfamily M, member 1
chr12_-_44670632	0.316	NM_004719	SCAF11	SR-related CTD-associated factor 11
chr1_-_33275057	0.314	NM_001625	AK2	adenylate kinase 2
chr2_-_85435074	0.311	NM_017750	RETSAT	retinol saturase (all-trans-retinol 13,14-reductase)
chr8_+_110415725	0.301	NM_001193557 NM_020189	ENY2	enhancer of yellow 2 homolog (Drosophila)
chr17_-_77616968	0.301	NM_022156	DUS1L	dihydrouridine synthase 1-like (S. cerevisiae)
chr20_-_42713663	0.301		ADA	adenosine deaminase
chr18_-_23019176	0.298	NM_031422	CHST9	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr11_-_133628348	0.297	NM_001037304 NM_001037305 NM_014174 NM_199297 NM_199298	THYN1	thymocyte nuclear protein 1
chr9_+_111582317	0.297	NM_053016 NM_007203 NM_147150	PALM2 PALM2-AKAP2	paralemmin 2 PALM2-AKAP2 readthrough
chr19_+_58239802	0.296	NM_001191055	HERV-V2	envelope glycoprotein ENVV2
chr16_+_74901235	0.294	NM_138994	CNTNAP4	contactin associated protein-like 4
chr12_-_12182641	0.291		LRP6	low density lipoprotein receptor-related protein 6
chr2_+_69974581	0.290	NM_006857	SNRNP27	small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
chr13_-_24395054	0.288	NM_018451	CENPJ	centromere protein J
chr17_-_7083321	0.288	NM_024297	PHF23	PHD finger protein 23
chr10_+_93548119	0.280	NM_025235	TNKS2	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr19_-_63119746	0.280	NM_152475	ZNF417	zinc finger protein 417
chr10_-_38305458	0.279	NM_145011	ZNF25	zinc finger protein 25
chr19_+_45168872	0.279	NM_006503 NM_153001	PSMC4	proteasome (prosome, macropain) 26S subunit, ATPase, 4
chr19_-_42777486	0.277	NM_016536	ZNF571	zinc finger protein 571
chr11_-_33678861	0.276	NM_001166692	C11orf91	chromosome 11 open reading frame 91
chr17_-_77616953	0.276		DUS1L	dihydrouridine synthase 1-like (S. cerevisiae)
chr1_-_158883666	0.274	NM_003037	SLAMF1	signaling lymphocytic activation molecule family member 1
chr5_+_140733664	0.271	NM_018919 NM_032086	PCDHGA6	protocadherin gamma subfamily A, 6
chr19_-_49644470	0.268	NM_014518	ZNF229	zinc finger protein 229
chr3_-_132228273	0.264	NM_014065	ASTE1	asteroid homolog 1 (Drosophila)
chr7_+_92699588	0.262	NM_017667 NM_024553	CCDC132	coiled-coil domain containing 132
chr12_-_61832856	0.253	NM_000706	AVPR1A	arginine vasopressin receptor 1A
chr8_+_27687821	0.252	NM_001017420	ESCO2	establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr1_+_246703249	0.252	NM_001005495	OR2T3	olfactory receptor, family 2, subfamily T, member 3
chr17_+_30938470	0.252		AP2B1	adaptor-related protein complex 2, beta 1 subunit
chr17_+_5264195	0.251		RPAIN	RPA interacting protein
chr12_+_21175394	0.250	NM_006446	SLCO1B1	solute carrier organic anion transporter family, member 1B1
chr3_-_52163745	0.246	NM_001161580 NM_001161581 NM_015426	POC1A	POC1 centriolar protein homolog A (Chlamydomonas)
chr19_-_52045890	0.245	NM_004069 NM_021575	AP2S1	adaptor-related protein complex 2, sigma 1 subunit
chr9_-_112139908	0.244	NM_001003936	TXNDC8	thioredoxin domain containing 8 (spermatozoa)
chr5_+_175597943	0.242	NM_198567	C5orf25	chromosome 5 open reading frame 25
chr1_-_153379344	0.237	NM_018973 NM_153741	DPM3	dolichyl-phosphate mannosyltransferase polypeptide 3
chr2_-_230792844	0.234	NM_004509 NM_004510 NM_080424	SP110	SP110 nuclear body protein
chr10_-_121346464	0.233		TIAL1	TIA1 cytotoxic granule-associated RNA binding protein-like 1
chr17_+_30938433	0.229		AP2B1	adaptor-related protein complex 2, beta 1 subunit
chr1_+_148020869	0.226	NM_000566	FCGR1A	Fc fragment of IgG, high affinity Ia, receptor (CD64)
chr11_+_85690900	0.224	NM_016401	C11orf73	chromosome 11 open reading frame 73
chr20_-_47963682	0.224	NM_001135773	SPATA2	spermatogenesis associated 2
chr7_-_44579787	0.219		DDX56	DEAD (Asp-Glu-Ala-Asp) box polypeptide 56
chr2_+_48649662	0.219	NM_172311	STON1-GTF2A1L	STON1-GTF2A1L readthrough
chr8_-_109330116	0.218	NM_001568	EIF3E	eukaryotic translation initiation factor 3, subunit E

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.08	6.82e-08	GO:0006355	regulation of transcription, DNA-dependent
1.97	3.56e-07	GO:2000112	regulation of cellular macromolecule biosynthetic process
2.01	4.46e-07	GO:0051252	regulation of RNA metabolic process
1.94	5.72e-07	GO:0010556	regulation of macromolecule biosynthetic process
1.86	5.71e-06	GO:0010468	regulation of gene expression
1.83	7.40e-06	GO:0009889	regulation of biosynthetic process
1.83	9.36e-06	GO:0031326	regulation of cellular biosynthetic process
1.79	1.84e-05	GO:0051171	regulation of nitrogen compound metabolic process
1.81	2.02e-05	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.67	5.81e-05	GO:0060255	regulation of macromolecule metabolic process
1.57	1.45e-03	GO:0080090	regulation of primary metabolic process
1.56	1.49e-03	GO:0031323	regulation of cellular metabolic process
1.47	1.29e-02	GO:0019222	regulation of metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.28	1.79e-06	GO:0043229	intracellular organelle
1.48	2.17e-06	GO:0005634	nucleus
1.28	2.19e-06	GO:0043226	organelle
1.30	5.77e-06	GO:0043231	intracellular membrane-bounded organelle
1.30	6.44e-06	GO:0043227	membrane-bounded organelle
1.18	1.22e-03	GO:0044424	intracellular part
1.16	6.66e-03	GO:0005622	intracellular
6.79	4.93e-02	GO:0005932	microtubule basal body

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
2.26	4.26e-13	GO:0046914	transition metal ion binding
2.36	5.66e-13	GO:0008270	zinc ion binding
2.10	4.35e-10	GO:0003677	DNA binding
1.69	4.16e-08	GO:0046872	metal ion binding
1.67	8.77e-08	GO:0043169	cation binding
1.67	1.03e-07	GO:0043167	ion binding
1.65	1.48e-05	GO:0003676	nucleic acid binding